Surprised that no one's made this yet. For me it's
1. Witcher 2, XBox port. I hear nothing but great things about this game. I don't have a PC for gaming, so I'm glad it's coming to one of the consoles.
2. Journey. Even though I wasn't a huge fan of Flow and some aspects of Flower actively annoyed me, what I've read about this sounds pretty fascinating.
3. The Last Guardian. Again, even though I thought Ico was only o.k. and I've decided not to play Shadow of the Colossus,
SPOILER: (highlight to read)
not interested in committing genocide and bringing someone back from the dead is never a good idea,
I'm still interested in seeing what Team Ico comes up with next.
4. I'm going to predict that I'll excited for Mass Effect 3 if I get around to playing 1 and 2 before March.