I looked at the map and read through her tweets. I hope it isn't going to be as bad as she makes it out.
1. Most people have pre-registered and will already have their badge mailed to them. I don't think registration will be very bad. It's kind of a bummer for cosplay gatherings that use site 6 since the new site 6 is in the trees area where there's normally a crowd of people hanging out in the shade.
2. The new shuttle bus pickup/drop off area could be a traffic jam, but I'm hoping the con planned for that. West Rd., just south of the movie theater is pretty small and at peak times with buses and long lines they'll probably have to close off the street. From what I remember Chick Hearn Ct. is closed between Microsoft and Staples during the day already.
I normally ride the Metro blue line so the shuttle isn't a big deal for me.